What are the benefits of animal IVP?

Recent data collected by the International Embryo Technology Society (IETS) has shown the global shift in popularity and usage from traditional methods in favour of novel, in vitro technologies to produce embryos.

More and more clinics are making the switch to in vitro production (IVP) and it is easy to see why. Some of the key benefits of IVP as a reproductive tool are:

Uterus diagram

Overcome physiological problems

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Overcome physiological problems

IVF can be used to produce offspring from elite animals that are non-productive in traditional methods. The reasons could be abnormal or damaged reproductive tracts, poor response to stimulation or idiopathic reasons.

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Preserve valuable genetics

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Preserve valuable genetics

Genetically elite animals can be repeatedly used as egg donors and the embryos produced transferred into less valuable animals, producing offspring with favourable genetics. In the case of the unexpected death / slaughter of a valuable animal, eggs can be rescued from the ovaries and the resultant embryos can be transferred into recipients.

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Shorter generational interval

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Shorter generational interval

Typically, donor oocytes can be aspirated on a two-week cycle whereas most embryo transfer (ET) programmes operate on a 60 day cycle. This allows for increased propagation of premium livestock.

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Wider variety of donors

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Wider variety of donors

Eggs can be aspirated from a wide variety of donors, such as pre-pubertal and juvenile heifers and transferred to recipients. Pregnant animals (up to 100 days gestation) can also be used as donors with excellent success rates and without any harm to the developing calf.

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Reduced cost of semen

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Reduced cost of semen

As fertilisation takes place in a microscopic environment, significantly less semen is needed to fertilise the same number of eggs. This is highly beneficial when a rare, expensive and / or sexed semen sample is used.

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Less hormone reliance

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Less hormone reliance

Growing evidence supports moving away from administering expensive super-ovulatory drugs, as maturation can successfully be performed in vitro. Therefore, donor animals are not exposed to any potentially harmful side effects due to these hormones.

How achievable is animal IVP?

Outsourcing IVP to larger companies has been the default option in the past, but advances in the market have made in-house IVP an increasingly workable and affordable solution. The commercial availability of our media for animal IVF also means that you can save up to $15,000 on the initial start-up cost of your IVF lab1.

Based upon our recommended media consumptions, the cost of media per embryo is in the region of $10-15. With our extensive quality control tests, industry leading shelf lives and dedicated product support; we work with you every step of the way to maximise your profitability and accelerate your herd’s genetics.

Establishing an animal IVF laboratory is easier than you might think, especially if you already have embryo transfer facilities, equipment and experience. A typical start-up animal IVF laboratory will need:

  • Laminar flow hood
  • Incubators
  • Centrifuge
  • Stereomicroscope
  • Refrigerator

We can provide you with expert recommendations on suitable lab equipment, consumables and standard operating procedures. You may also benefit from attending one of our training courses to experience a fully operational animal IVF laboratory. In the meantime, please watch our protocol videos to understand the IVF Bioscience process in greater detail.

1estimate based on accrued cost of media-manufacturing equipment (pH meter, osmometer, analytical scales etc.) as well as raw ingredients and consumables for the first year.

Protocols of Interest, tick all that apply *
Bovine
Bovine On-site commercial protocolBovine Off-site commercial protocolBovine Slaughterhouse trial protocolBovine Vitrification protocol
Equine
Equine Slaughterhouse trial protocolEquine Commercial protocolEquine Vitrification protocol

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In Vitro Maturation

Semen Preparation

In Vitro Fertilisation

In Vitro Embryo Culture

Genetic Improvement

With global population estimated to reach almost 10 billion by 2050, consumer demand for meat and dairy produce is expected to exponentially increase. Therefore, livestock with superior genetics (i.e. larger milk and meat yields) need to be bred with shorter generational intervals to increase food production and reduce animal wastage.

Historically, genetically valuable animals have been bred by ‘flushing’ embryos created via artificial insemination (AI) and multiple ovulation embryo transfer (MOET). Embryos produced and transferred via these techniques are known as in vivo derived (IVD). However, new technologies have disrupted the market and provide excellent benefits for all involved in the industry.

What is IVP?

In vitro embryo production, also referred to as in vitro fertilisation (IVF), is the process of creating embryos by fertilising mature oocytes with sperm outside of the uterus i.e. in a dish.

Oocytes are collected from anaesthetised donors by ultrasound-guided follicular aspiration (ovum pick-up – OPU).

The donor oocytes are then matured in an incubator for 21-24 hours before being fertilised via the addition of sperm.

The inseminated oocytes are then cultured further in an incubator for up to seven days, at which point the resulting viable embryos are transferred into recipients or frozen for future use.

Additionally, embryos can be biopsied to determine the genetic make-up and/ or sex of each embryo.

OPU-IVP process explained

Why IVF Bioscience?

Our advanced, serum-free media suite is provided in combination with optimised IVF and ICSI protocols backed by continuous technical support. We work with you every step to ensure you get the best results possible.

All IVF Bioscience products are manufactured to the same standard applied to human IVF media production and each batch will undergo extensive quality control testing before release.

There are a number of challenges to overcome when setting up a successful animal IVF laboratory. Thankfully, we can now say there is one less.

Our Complete IVP Media Suite

All of our products are ready to use*, serum-free and offer an industry leading shelf life

*Due to import regulations, some products shipped to Australia and New Zealand will be BSA-free, where BSA supplementation will be required by the end user.

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